The Smith Lab studies protein structure and dynamics using a combination of computer simulation and nuclear magnetic resonance (NMR) spectroscopy. We are particularly interested in optimizing the dynamics of computationally designed proteins and understanding how mutations allosterically affect the functions of natural proteins.

Colin Smith is a member of the Chemistry department at Wesleyan University. He is also affiliated with the Molecular Biophysics program, the Molecular Biology and Biochemistry department, and the College of Integrative Sciences.

We are located on the third floor of the Casper Life Sciences building. The wet lab is in room A310, dry lab in A300, and Colin’s office in room A309.

Our research is supported by a National Science Foundation CAREER Award, the National Institutes of Health, NSF ACCESS/XSEDE supercomputer time, and the Rosetta Commons.

Address:

Smith Lab
Wesleyan University
Casper Life Sciences Building
16 Lawn Avenue
Middletown, CT 06459